Microglial P2Y6 calcium signaling promotes phagocytosis and shapes neuroimmune responses in epileptogenesis
Anthony D. Umpierre, Bohan Li, Katayoun Ayafsoufi, Whitney L. Simon, Shunyi Zhao, Manling Xie , Grace Thyen, Benjamin Hur, Jiaying Zheng, Yue Liang, Dale B. Bosco Mark A. Maynes, Zhaofa Wu, Xinzhu Yu, Jaeyun Sung, Aaron J. Johnson, Yulong Li, Long-Jun Wu
Neuron, 2024, PMID: 38614103
Tuning neural circuits and behaviors by microglia in the adult brain
Shunyi Zhao, Anthony D. Umpierre, Long-Jun Wu
Trends in Neurosciences, 2024, PMID: 38245380
Microglia enhance post-anesthesia neuronal activity by shielding inhibitory synapses
Koichiro Haruwaka, Yanlu Ying, Yue Liang, Anthony D. Umpierre, Min Hee Yi, Vaclav Kremen, Tingjun Chen, Tao Xie, Fangfang Qi, Shunyi Zhao, Jiaying Zheng, Yong U. Liu, Hailong Dong, Gregory A. Worrell, Long Jun Wu
Nature Neuroscience, 2024, PMID: 38177340
How microglia sense and regulate neuronal activity
Anthony D. Umpierre, Long-Jun Wu
Glia, 2021, PMID: 33369790
Microglial calcium signaling is attuned to neuronal activity in awake mice
Anthony D. Umpierre, Lauren L. Bystrom, Yanlu Ying, Yong U. Liu, Gregory Worrell, Long-Jun Wu
eLife, 2020, PMID: 32716294
Neuronal network activity controls microglial process surveillance in awake mice via norepinephrine signaling
Yong U. Liu, Yanlu Ying, Yujiao Li, Ukpong B. Eyo, Tingjun Chen, Jiaying Zheng, Anthony D. Umpierre, Jia Zhu, Dale B. Bosco, Hailong Dong, Long Jun Wu
Nature Neuroscience, 2019, PMID: 31636449
Conditional Knock-out of mGluR5 from Astrocytes during Epilepsy Development Impairs High-Frequency Glutamate Uptake
Anthony D. Umpierre, Peter J. West, John A. White, Karen S. Wilcox
Journal of Neuroscience, 2019, PMID: 30504280
Repeated low-dose kainate administration in C57BL/6J mice produces temporal lobe epilepsy pathology but infrequent spontaneous seizures
Anthony D. Umpierre, Isaiah V. Bennett, Lismore D. Nebeker, Thomas G. Newell, Bruce B. Tian, Kyle E. Thomson, H Steve White, John A. White, Karen S. Wilcox
Experimental Neurology, 2016, PMID: 26896834
Impaired cognitive ability and anxiety-like behavior following acute seizures in the Theiler’s virus model of temporal lobe epilepsy
Anthony D. Umpierre, Gregory J. Remigio, E Jill Dahle, Kate Bradford, Anitha B. Alex, Misty D. Smith, Peter J. West, H Steve White, Karen S. Wilcox
Neurobiology of Disease, 2014, PMID: 24412221
For a list of all PI and lab publications, please see https://www.ncbi.nlm.nih.gov/myncbi/anthony.umpierre.1/bibliography/public/
The Umpierre Lab 